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Description

Labisia pumila (Kacip Fatimah) is a traditional herb commonly used by Malay women during peripartum period to make the process of childbirth easier and also during postpartum period to improve general condition of mother. Earlier research on Labisia pumila showed that it has estrogenic-like effect. This randomized, placebo controlled study was designed to look at the safety profile of Labisia pumila water extract on postmenopausal women. Pre-study screening and assessment was done and if subject is eligible, informed consent taken and baseline investigation was taken including hematological, liver and renal function, chest x-ray, ECG, mammography and pap smear. The study duration was six month and all participants were required to come for visit every two month. During each visit participants were asked regarding any side effects of medication or occurrence of per vaginal bleeding. Vital signs, body mass index and waist hip ratio were measured on every visit. On visit 4 or last visit, all blood investigations, chest x- ray, ECG and pap smear were repeated. As a conclusion we found that Labisia pumila water extract was safe for consumption.