Description

This book consist of development of Mycobacterium tuberculosis inhibitors through insilico approach such as design of side chain analogues through combinatorial approach. The designed analogues have good ADMET properties and Lipinski's drug like criterion and may be used as newer candidate for Tuberculosis. Apart from development of analogues the 3D model of RmlA protein responsible for the formation of mycolic acid was built and various designed analogues were screened through it, that yielded few potential inhibitors against RmlA.

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