Description

Drug therapy is a dynamic process. Oral route of drug delivery is typically considered the preferred and the most patient-convenient means of drug administration. Among the drugs that are administered orally, solid oral dosage forms represents the preferred choice of class of product. Commonly used solid oral dosage forms are tablets and capsules; tablets are indeed the most popular solid dosage form for oral administration. In recent years a wide variety of newer oral drug delivery systems like controlled/ sustained release dosage forms are designed and evaluated in order to overcome the limitation of conventional therapy. These products are able to maintain steady drug plasma levels for extended periods of time as a result the variation of drug levels in the blood are prevented and minimized drug related side effects. Multiparticulate dosage forms are pharmaceutical formulations in which the active substance is present as a number of small independent subunits with diameter of 0.05-2.00 mm and widely accepted as a means to achieve oral and parenteral controlled release.